During a presentation of the game by Troy Baker and Michael De Plater, Shadow of War's Creative Lead, it was revealed missions will not be replayable if the player dies, The Escapist reports.
As sometimes happens during live presentations, the protagonist was killed during the demo, which prompted De Plater to state, "we can never replay that mission, 'cause time's gonna move forward, the world's gonna evolve, the guys that're dead are gonna stay dead"..."so the world constantly moves forward."
The previous game, Shadow of Mordor, also had permanent consequences to death; orcs who killed you would get stronger, and orcs you killed would remember you - features which will return in the sequel. So it looks like Monolith are expanding on the permanency from the original game with even harsher features.
How exactly this system will work hasn't been revealed however; whether a lost mission is actually lost forever, or if they'll simply show-up somewhere else in a different form.
Shadow of War is releasing for PS4, Xbox One and PC on October 10.